Purpura Children

Purpura children

        Purpura is a skin eruption of petechiae made as large as a pinhead, red at first, corresponding to tiny spots of blood under the skin. These elements do not disappear when are pressed with a finger unlike measles or rubella. Bruising and bleeding of mucous membranes are often associated. These signs are due to the fall in the number of platelets in the blood (thrombocytopenia).Platelets are cells that help clotting. The normal number is around 300 000 platelets / mm 3. In practice, the bleeding mucosal can occur for platelet counts below 50 000 / mm3. The bleeding time (TS) is increased.

The decrease rate of platelets in the blood can come from:

• To decrease the production of platelets marrow (leukemia, aplastic anemia etc.);
• In accelerated destruction of circulating platelets during infection (viral hepatitis, measles, rubella, chickenpox, mumps, infectious mononucleosis, typhoid fever, toxoplasmosis, malaria ...), as a result of immuno-allergic phenomena (after taking quinine, phenobarbital, penicillamine, phenylbutazone, aspirin, thiazide, indomethacin, heparin, subcutaneous heparin, Buscopan, phenytoin, carbamazepine, clonazepam, sodium valproate, primidone, nitrofurantoin, gold salts, sulfonamides, antibiotics ampicillin, tetracycline , rifampicin, penicillin, Cephalothin etc. ..).

Purpura children pictures

        The Wiskott-Aldrich is a familial disease, recessive X-linked, including eczema, thrombocytopenic purpura and a tendency to recurrent infections. In the absence of specific treatment, therapy includes antibiotics and platelet transfusions. The removal of the spleen corrects the thrombocytopenia but increases the risk of infections. Marrow transplantation is sometimes attempted. Evolution is serious.